C6 L-threo Ceramide
C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides[1]. C6 L-threo Ceramide significantly inhibits IL-4 production in T cells. Anti-allergic agents[2].
Product Specifications
CAS Number
189894-80-2
UNSPSC
12352211
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/c6-l-threo-ceramide.html
Solubility
10 mM in DMSO
Smiles
OC[C@H](NC(CCCCC)=O)[C@H](/C=C/CCCCCCCCCCCCC)O
Molecular Formula
C24H47NO3
Molecular Weight
397.63
References & Citations
[1]Jin Park, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13 (7) :2589-95.|[2]Jin Park, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13 (7) :2589-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-4
Frequently Asked Questions
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