AF710B
AF710B is a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B can be used for the research of Alzheimer’s disease[1].
Product Specifications
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/af710b.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]1SC2(CN1C(CCC3=CNC4=C3C=CC=C4)=O)CCN(CC2)C
Molecular Formula
C20H27N3OS
Molecular Weight
357.51
References & Citations
[1]Fisher A, et al. AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease. Neurodegener Dis. 2016;16 (1-2) :95-110.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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