Rilmakalim
Rilmakalim (HOE 234) is a potassium channel opener (PCO) that activates ATP-sensitive K+ channels in the heart or other tissues[1].
Product Specifications
CAS Number
[132014-21-2]
Product Name Alternative
HOE 234
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rilmakalim.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CCC1)[C@H]2[C@@H](C(C)(OC3=C2C=C(C=C3)S(=O)(C4=CC=CC=C4)=O)C)O
Molecular Formula
C21H23NO5S
Molecular Weight
401.48
References & Citations
[1]Kocic, Ivan et al. Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K (+) current in guinea pig ventricular myocytes. Journal of pharmacological sciences vol. 95,2 (2004) : 189-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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