Piroheptine (hydrochloride)

Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608) . Piroheptine hydrochloride can be used for research in Parkinson[1].

Product Specifications

CAS Number

[16378-22-6]

UNSPSC

12352005

Target

Dopamine Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/piroheptine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CCN1C(/C(CC1)=C2C3=C(CCC4=C/2C=CC=C4)C=CC=C3)C.Cl

Molecular Formula

C22H26ClN

Molecular Weight

339.90

References & Citations

[1]Saitoh T. Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl. J Neurol Sci. 1988 Feb;83 (2-3) :161-6.