Piroheptine (hydrochloride)
Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP. Piroheptine hydrochloride can be used for research in Parkinson[1].
Product Specifications
CAS Number
16378-22-6
UNSPSC
12352005
Target
Dopamine Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/piroheptine-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CCN1C(/C(CC1)=C2C3=C(CCC4=C/2C=CC=C4)C=CC=C3)C.Cl
Molecular Formula
C22H26ClN
Molecular Weight
339.90
References & Citations
[1]Saitoh T. Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced dopaminergic neurotoxicity in mouse brain by piroheptine and trihexyphenidyl. J Neurol Sci. 1988 Feb;83 (2-3) :161-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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