RMM-46
RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].
Product Specifications
CAS Number
[1307896-46-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
MAPKAPK2 (MK2)
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rmm-46.html
Solubility
10 mM in DMSO
Smiles
O=C(/C(C#N)=C/C1=CC2=C(C=C1)NN=C2C3=CC(OC)=C(C(OC)=C3)OC)NC(C)(CO)C
Molecular Formula
C24H26N4O5
Molecular Weight
450.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Miller RM, et al. Electrophilic fragment-based design of reversible covalent kinase inhibitors. J Am Chem Soc. 2013 Apr 10;135 (14) :5298-301.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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