Propanidid
Propanidid (Sombrevin; Fabantol) is a γ-aminobutyric acid type A (GABAA) receptor agonist and a short-acting non-barbiturate general agent that can suppress or relieve pain. Propanidid can decrease the arterial pressure[1][2].
Product Specifications
CAS Number
1421-14-3
Product Name Alternative
Sombrevin; Fabantol
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/propanidid.html
Purity
98.19
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CC1=CC=C(C(OC)=C1)OCC(N(CC)CC)=O)OCCC
Molecular Formula
C18H27NO5
Molecular Weight
337.41
References & Citations
[1]Cenani A, et al. In vitro and in vivo GABAA Receptor Interaction of the Propanidid Metabolite 4- (2-[Diethylamino]-2-Oxoethoxy) -3-Methoxy-Benzeneacetic Acid. Pharmacology. 2019;103 (1-2) :10-16.|[2]Orko R. Anaesthesia for cardioversion: a comparison of diazepam, thiopentone and propanidid. Br J Anaesth. 1976 Mar;48 (3) :257-62.|[3]Lazareva NA, et al. The effect of sombrevin on the orientation adjustment of the visual cortex neurons in the cat. Neirofiziologiia. 1989;21 (6) :812-20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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