Clathrodin
Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance[1][2].
Product Specifications
CAS Number
135383-64-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clathrodin.html
Solubility
10 mM in DMSO
Smiles
O=C(NC/C=C/C1=CN=C(N1)N)C2=CC=CN2
Molecular Formula
C11H13N5O
Molecular Weight
231.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Rentas AL, et al. Effect of alkaloid toxins from tropical marine sponges on membrane sodium currents. Toxicon. 1995 Apr;33 (4) :491-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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