Nequinate
Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections[1]. Nequinate inhibits xanthine oxidoreductase (XOD) activity[2].
Product Specifications
CAS Number
13997-19-8
UNSPSC
12352005
Hazard Statement
H302-H413
Target
Parasite; Xanthine Oxidase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nequinate.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CNC2=C(C=C(CCCC)C(OCC3=CC=CC=C3)=C2)C1=O)OC
Molecular Formula
C22H23NO4
Molecular Weight
365.42
Precautions
P264-P270-P273-P330-P501
References & Citations
[1]D K McLoughlin, et al.Efficacy of Nequinate Against Thirteen Strains of Eimeria Tenella and the Development of a Nequinate-Resistant Strain.Avian Dis. Oct-Dec 1973;17 (4) :717-21.|[2]Yanfen Niu, et al. Old Drug, New Indication: Olsalazine Sodium Reduced Serum Uric Acid Levels in Mice via Inhibiting Xanthine Oxidoreductase Activity. J Pharmacol Sci. 2017 Nov;135 (3) :114-120.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Coccidia
Available Sizes
Frequently Asked Questions
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