Nequinate

Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections[1]. Nequinate inhibits xanthine oxidoreductase (XOD) activity[2].

Product Specifications

CAS Number

[13997-19-8]

UNSPSC

12352005

Hazard Statement

H302-H413

Target

Parasite; Xanthine Oxidase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/nequinate.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CNC2=C(C=C(CCCC)C(OCC3=CC=CC=C3)=C2)C1=O)OC

Molecular Formula

C22H23NO4

Molecular Weight

365.42

Precautions

P264-P270-P273-P330-P501

References & Citations

[1]D K McLoughlin, et al.Efficacy of Nequinate Against Thirteen Strains of Eimeria Tenella and the Development of a Nequinate-Resistant Strain.Avian Dis. Oct-Dec 1973;17 (4) :717-21.|[2]Yanfen Niu, et al. Old Drug, New Indication: Olsalazine Sodium Reduced Serum Uric Acid Levels in Mice via Inhibiting Xanthine Oxidoreductase Activity. J Pharmacol Sci. 2017 Nov;135 (3) :114-120.