ICI D1542
ICI D1542 is a selective and potent inhibitor of thromboxane A2 (TXA2) synthase and the thromboxane A2 receptor (TP-receptor) . ICI D1542 is effective at preventing thrombus formation by redirection of arachidonic acid metabolism[1].
Product Specifications
CAS Number
147332-48-7
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ici-d1542.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CC/C=C\C[C@H]1[C@@H](C2=CC=CN=C2)O[C@@H](C(OC3=CC=C(C)C=C3[N+]([O-])=O)(C)C)OC1
Molecular Formula
C25H30N2O7
Molecular Weight
470.51
References & Citations
[1]S J McAuliffe, et al. Redirection of arachidonic acid metabolism by ICI D1542: effects on thrombus formation in the coronary artery of the anaesthetized dog. r J Pharmacol. 1993 Apr;108 (4) :901-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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