HJC0149
Product Specifications
UNSPSC Description
HJC0149 is a potent and orally active inhibitor of signal transducer and activator of transcription 3 (STAT3)[1].
Target Antigen
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hjc0149.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=C(C=C1)Cl)C(NC2=CC3=C(C=C2)C=CS3(=O)=O)=O
Molecular Weight
335.76
References & Citations
[1]Chen H, et al. Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3). Eur J Med Chem. 2014;82:195-203.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116278/HJC0149-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116278/
Clinical Information
No Development Reported
CAS Number
1430330-65-6
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