HJC0149
HJC0149 is a potent and orally active inhibitor of signal transducer and activator of transcription 3 (STAT3) [1].
Product Specifications
CAS Number
[1430330-65-6]
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hjc0149.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=C(C=C1)Cl)C(NC2=CC3=C(C=C2)C=CS3(=O)=O)=O
Molecular Formula
C15H10ClNO4S
Molecular Weight
335.76
References & Citations
[1]Chen H, et al. Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3) . Eur J Med Chem. 2014;82:195-203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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