L-157012
Product Specifications
UNSPSC Description
L-157012 is a HMG-CoA reductase (HMGCR) inhibitor. L-157012 is also a cholesterol-lowering agent[1].
Target Antigen
HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-157012.html
Solubility
10 mM in DMSO
Smiles
CC[C@H](C)C(O[C@H]1C[C@@H](C=C2C=C[C@@H]([C@@H]([C@@]12[H])CC[C@@]3([H])OC(C[C@H](O)C3)=O)C)CO)=O
Molecular Weight
420.54
References & Citations
[1]Kaufman MJ. Applications of oxygen polarography to drug stability testing and formulation development: solution-phase oxidation of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. Pharm Res. 1990 Mar;7(3):289-92.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116241/L-157012-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116241/
Clinical Information
No Development Reported
CAS Number
114801-28-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6469136-01 0.1 mL
CIT, ID (Citron Rho-interacting Kinase, CRIK, Serine/Threonine-protein Kinase 21, KIAA0949, STK21) (MaxLight 405)
Ask
View Details 
MBS6469136-02 5x 0.1 mL
CIT, ID (Citron Rho-interacting Kinase, CRIK, Serine/Threonine-protein Kinase 21, KIAA0949, STK21) (MaxLight 405)
Ask
View Details 