L-157012
L-157012 is a HMG-CoA reductase (HMGCR) inhibitor. L-157012 is also a cholesterol-lowering agent[1].
Product Specifications
CAS Number
[114801-28-4]
UNSPSC
12352005
Target
HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-157012.html
Solubility
10 mM in DMSO
Smiles
CC[C@H](C)C(O[C@H]1C[C@@H](C=C2C=C[C@@H]([C@@H]([C@@]12[H])CC[C@@]3([H])OC(C[C@H](O)C3)=O)C)CO)=O
Molecular Formula
C24H36O6
Molecular Weight
420.54
References & Citations
[1]Kaufman MJ. Applications of oxygen polarography to drug stability testing and formulation development: solution-phase oxidation of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. Pharm Res. 1990 Mar;7 (3) :289-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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