L-157012

L-157012 is a HMG-CoA reductase (HMGCR) inhibitor. L-157012 is also a cholesterol-lowering agent[1].

Product Specifications

CAS Number

[114801-28-4]

UNSPSC

12352005

Target

HMG-CoA Reductase (HMGCR)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/l-157012.html

Solubility

10 mM in DMSO

Smiles

CC[C@H](C)C(O[C@H]1C[C@@H](C=C2C=C[C@@H]([C@@H]([C@@]12[H])CC[C@@]3([H])OC(C[C@H](O)C3)=O)C)CO)=O

Molecular Formula

C24H36O6

Molecular Weight

420.54

References & Citations

[1]Kaufman MJ. Applications of oxygen polarography to drug stability testing and formulation development: solution-phase oxidation of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitors. Pharm Res. 1990 Mar;7 (3) :289-92.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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