ROCK-IN-D2
Product Specifications
UNSPSC Description
ROCK-IN-D2 is a potent and selective ROCK inhibitor[1].
Target Antigen
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
others
Assay Protocol
https://www.medchemexpress.com/rock-in-d2.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=CC=C1)NC2=C(C=C(C=C2)C3=CNN=C3)N(C)CCN(C)C
Molecular Weight
392.50
References & Citations
[1]Ding Mei, et al. Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor’s potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.Bioorg Med Chem. 2015 May 15;23(10):2505-17.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116238/ROCK-IN-D2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116238/
Clinical Information
No Development Reported
CAS Number
1219721-78-4
Curated Selection
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