Gemifloxacin

Gemifloxacin, a fluoroquinolone, is a potent and orally active antipneumococcal agent. Gemifloxacin shows bactericidal activity against highly quinolone-resistant pneumococci.Gemifloxacin can be used for the research of respiratory infections, such as community-acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB) [1][2].

Product Specifications

CAS Number

[175463-14-6]

Product Name Alternative

SB-265805; LB20304

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gemifloxacin.html

Solubility

10 mM in DMSO

Smiles

NCC(C1)/C(CN1C(N=C2C(C(C(C(O)=O)=CN2C3CC3)=O)=C4)=C4F)=N/OC

Molecular Formula

C18H20FN5O4

Molecular Weight

389.38

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Yoo BK, et al. Gemifloxacin: a new fluoroquinolone approved for treatment of respiratory infections. Ann Pharmacother. 2004 Jul-Aug;38 (7-8) :1226-35.|[2]Davies TA, et al. Antipneumococcal activities of gemifloxacin compared to those of nine other agents. Antimicrob Agents Chemother. 2000 Feb;44 (2) :304-10.