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Oosponol

Oosponol is a dopamine beta-hydroxylase inhibitor exhibiting hypotensive effects.Oospongol has strong antifungal activity against many antagonistic fungi[1][2].

Product Specifications

CAS Number

[146-04-3]

UNSPSC

12352005

Target

Dopamine β-hydroxylase; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/oosponol.html

Solubility

10 mM in DMSO

Smiles

O=C1OC=C(C2=C1C(O)=CC=C2)C(CO)=O

Molecular Formula

C11H8O5

Molecular Weight

220.18

References & Citations

[1]Umezawa H, et al.. Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. J Antibiot (Tokyo) . 1972 Apr;25 (4) :239-42.|[2]Sonnenbichler J, et al. Influence of the Gloeophyllum metabolite oosponol and some synthetic analogues on protein and RNA synthesis in target cells. Eur J Biochem. 1997 May 15;246 (1) :45-9.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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