VU0404251

VU0404251 is a highly potent positive allosteric modulator of mGlu for the study of psychosis[1].

Product Specifications

CAS Number

1276013-77-4

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/vu0404251.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](C)C(C)(C)C)C1=CC=C(N=C1)OCC2=CC=CC(F)=C2

Molecular Formula

C19H23FN2O2

Molecular Weight

330.40

References & Citations

[1]Manka JT, et al. Optimization of an ether series of mGlu5 positive allosteric modulators: molecular determinants of MPEP-site interaction crossover. Bioorg Med Chem Lett. 2012 Oct 15;22 (20) :6481-5.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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