GR 196429
GR 196429 is a melatonin receptor agonist with some selectivity for the MT1 subtype. GR 196429 produces both sleep-promoting effects and alterations of circadian rhythm, as well as stimulating melatonin release in mice[1].
Product Specifications
CAS Number
170729-12-1
UNSPSC
12352005
Target
Melatonin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gr-196429.html
Solubility
10 mM in DMSO
Smiles
CC(NCCN1CCC2=C1C3=C(C=C2)OCC3)=O
Molecular Formula
C14H18N2O2
Molecular Weight
246.30
References & Citations
[1]I J Beresford, et al. Pharmacological characterisation of melatonin mt1 receptor-mediated stimulation of [35S]-GTPgammaS binding. Biochem Pharmacol. 1998 Nov 1;56 (9) :1167-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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