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GR 196429

GR 196429 is a melatonin receptor agonist with some selectivity for the MT1 subtype. GR 196429 produces both sleep-promoting effects and alterations of circadian rhythm, as well as stimulating melatonin release in mice[1].

Product Specifications

CAS Number

170729-12-1

UNSPSC

12352005

Target

Melatonin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/gr-196429.html

Solubility

10 mM in DMSO

Smiles

CC(NCCN1CCC2=C1C3=C(C=C2)OCC3)=O

Molecular Formula

C14H18N2O2

Molecular Weight

246.30

References & Citations

[1]I J Beresford, et al. Pharmacological characterisation of melatonin mt1 receptor-mediated stimulation of [35S]-GTPgammaS binding. Biochem Pharmacol. 1998 Nov 1;56 (9) :1167-74.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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