Epiroprim
Epiroprim (Ro11-8958) is a selective dihydrofolate reductase (DHFR) inhibitor. Epiroprim displays excellent activity against staphylococci, enterococci, pneumococci, and streptococci[1].
Product Specifications
CAS Number
[73090-70-7]
Product Name Alternative
Ro11-8958
UNSPSC
12352005
Target
Bacterial; Dihydrofolate reductase (DHFR)
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/epiroprim.html
Solubility
10 mM in DMSO
Smiles
CCOC1=C(C(OCC)=CC(CC2=CN=C(N=C2N)N)=C1)N3C=CC=C3
Molecular Formula
C19H23N5O2
Molecular Weight
353.42
References & Citations
[1]H H Locher, et al. Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone. Antimicrob Agents Chemother. 1996 Jun;40 (6) :1376-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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