Carbonic anhydrase inhibitor 10
Product Specifications
UNSPSC Description
Carbonic anhydrase inhibitor 10 is a potent hCA IX inhibitor with a Ki value of 6.2 nM. Carbonic anhydrase inhibitor 10 exhibits anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 can be used for cancer research[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-10.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(C)=C(N=C1NC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)C
Molecular Weight
335.38
References & Citations
[1]Diaaeldin M Elimam, et al. Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Jan 15;228:114008.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115994/Carbonic-anhydrase-inhibitor-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115994/
Clinical Information
No Development Reported
CAS Number
2883453-30-1
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