Topoisomerase IV inhibitor 2
Selected Variant
HY-115991
Size: 1 Each
Topoisomerase IV inhibitor 2 (compound 5d) is a potent DNA topoisomerase IV (TOPO IV) inhibitor with IC50s of 0.35 μM and 0.55 μM for TOPO IV and DNA gyrase, respectively. Topoisomerase IV inhibitor 2 has anti-bacterial activity, with MICs of 1.985 μM and 0.744 μM in Staphylococcus aureus Newman and Escherichia coli ATCC8739, respectively[1].
Product Specifications
CAS Number
2883403-36-7
UNSPSC
12352005
Target
Bacterial; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/topoisomerase-iv-inhibitor-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C=C1)S(=O)(NC2=NC3=C(N=C2)C=CC=C3)=O)CN4CCN(CC4)C5=CC6=C(C(C(C(O)=O)=CN6C7CC7)=O)C=C5F
Molecular Formula
C33H30FN7O6S
Molecular Weight
671.70
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topoisomerase
Price
Frequently Asked Questions
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