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MAO-B-IN-5

MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC50 of 0.204 μM. MAO-B-IN-5 has the potential for the research of Parkinson's disease (PD) [1].

Product Specifications

CAS Number

849909-77-9

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mao-b-in-5.html

Solubility

10 mM in DMSO

Smiles

NC([C@@H]1CCCN1CC2=CC=C(C=C2)OCC3=CC(F)=CC=C3)=O

Molecular Formula

C19H21FN2O2

Molecular Weight

328.38

References & Citations

[1]Wang Z, et al. Enhancing monoamine oxidase B inhibitory activity via chiral fluorination: Structure-activity relationship, biological evaluation, and molecular docking study. Eur J Med Chem. 2022; 228:114025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MAO-A; MAO-B

Available Sizes

Frequently Asked Questions

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