GRPR antagonist-2
Product Specifications
UNSPSC Description
GRPR antagonist-2 is a potent gastrin releasing peptide receptor (GRPR) antagonist, having the cytotoxicity against certain cancer cells (IC50 of 0.77 and 2.5 μM in HGC-27 and Pan02 cells, respectively). Anticancer activity[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/grpr-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
CC(C)(OC(N1CCN(CC1)C([C@H](CC2=CNC3=C2C=CC=C3)NC(NC4=CC=C(C=C4)C(F)(F)F)=O)=O)=O)C
Molecular Weight
559.58
References & Citations
[1]Yu, Mj., et al. Structure–activity relationship studies on Pd176252 derivatives leading to discovery of novel GRP receptor antagonist with potent anticancer activity. Med Chem Res 30, 2069–2089 (2021).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115975/GRPR-antagonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115975/
Clinical Information
No Development Reported
CAS Number
3052544-42-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1323843-05 0.02 mg (Baculovirus)
Recombinant Shigella sonnei Protein SlyX (slyX)
Ask
View Details