Anticancer agent 36

Anticancer agent 36 (compound 11), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 36 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/L. Anticancer agent 36 inhibits A549, PC3 cell growth with IC50s of 19.7 µg/mL, 11.9 µg/mL, respectively[1].

Product Specifications

CAS Number

[2902563-76-0]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-36.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C=C1)S(=O)(NC(NC2=NC(C3=CC4=C(C=C3)C=CC=C4)=CS2)=O)=O

Molecular Formula

C21H17N3O3S2

Molecular Weight

423.51

References & Citations

[1]Farid M. Sroor, et al. Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies. Medicinal Chemistry Research volume 31, pages400–415 (2022) .