Anticancer agent 34

Anticancer agent 34 (compound 9), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 34 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/ml. Anticancer agent 34 inhibits A549, PC3 cell growth with IC50s of 8.4 µg/ml, 7.8 µg/ml, respectively[1].

Product Specifications

CAS Number

2379335-06-3

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-34.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(C)C=C1)(NC(NC2=NC(C3=CC=C(Br)C=C3)=CS2)=O)=O

Molecular Formula

C17H14BrN3O3S2

Molecular Weight

452.35

References & Citations

[1]Farid M. Sroor, et al. Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies. Medicinal Chemistry Research volume 31, pages400–415 (2022) .