EGFR/HER2-IN-3
EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual inhibitor of EGFR and HER2[1].
Product Specifications
CAS Number
1031620-09-3
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-her2-in-3.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C2=NN=C(C3=NC(NCC4=CC=C(OC)C=C4OC)=C5C=CC=CC5=N3)O2)C=C1
Molecular Formula
C26H23N5O3
Molecular Weight
453.49
References & Citations
[1]Sangande, et al. 2-substituted 4-aminoquinazoline derivatives as potential dual inhibitors of EGFR and HER2: an in silico and in vitro study. Medicinal Chemistry Research 31.5 (2022) : 762-771.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1; ErbB2/HER2
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