Antitumor agent-48
Product Specifications
UNSPSC Description
Antitumor agent-48 (Compound 4a) is a 2,3-dehydrosilybin derivative with an antitumor activity. Antitumor agent-48 shows cytotoxic activity against MCF-7, NCI-H1299, HepG2 and HT29 cells with IC50 values of 8.06 µM, 13.1 µM, 16.51 µM and 12.44 µM, respectively[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-48.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C2OC3=C(OC2CO)C=CC(C4=C(C(C5=C(C=C(C=C5O4)OC(N6CCOCC6)=O)O)=O)OC(N7CCOCC7)=O)=C3)=CC=C1O
Molecular Weight
706.65
References & Citations
[1]Qiuchan Wu, et al. Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups. Med Chem Res. 2022;31(4):533-544.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115950/Antitumor-agent-48-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115950/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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