Antitumor agent-47
Antitumor agent-47 (Compound 3e) is a silibinin derivative with an antitumor activity. Antitumor agent-47 shows cytotoxic activity against NCI-H1299 and HT29 cells with IC50 values of 8.07 µM and 6.27 µM, respectively[1].
Product Specifications
CAS Number
2917547-24-9
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-47.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C2OC3=C(OC2CO)C=CC(C4=C(C(C5=C(C=C(C=C5O4)OC(N6CCCC6)=O)O)=O)O)=C3)=CC=C1O
Molecular Formula
C30H27NO11
Molecular Weight
577.54
References & Citations
[1]Qiuchan Wu, et al. Synthesis and antitumor activity of novel silibinin and 2,3-dehydrosilybin derivatives with carbamate groups. Med Chem Res. 2022;31 (4) :533-544.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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