Anticancer agent 33
Anticancer agent 33 (compound 3), a Squamocin and Bullatacin derivative, is a potent anticancer agent. Anticancer agent 33 shows high potency to inhibit 4T1 breast cancer cell line (A549, HeLa, HepG2 and MCF-7 cells) growth with IC50s of 1.9-5.4 µM[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-33.html
Solubility
10 mM in DMSO
Smiles
CCCCCC[C@H](OC([C@@H]1CCCN1C(CNC(OC(C)(C)C)=O)=O)=O)CCC[C@@H]([C@H]2CC[C@@H](O2)[C@H]3CC[C@@H](O3)[C@@H](CCCCCCCCCCCCC4=C[C@@H](OC4=O)C)O)O
Molecular Formula
C49H84N2O11
Molecular Weight
877.20
References & Citations
[1]Jing-Fang Shi, et al. Synthesis and anticancer activity of Boc-Gly-Pro dipeptide-annonaceous acetogenin prodrugs targeting fibroblast activation protein or other hydrolytic enzymes. Medicinal Chemistry Research volume 31, pages605–616 (2022) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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