Anticancer agent 33

Anticancer agent 33 (compound 3), a Squamocin and Bullatacin derivative, is a potent anticancer agent. Anticancer agent 33 shows high potency to inhibit 4T1 breast cancer cell line (A549, HeLa, HepG2 and MCF-7 cells) growth with IC50s of 1.9-5.4 µM[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-33.html

Solubility

10 mM in DMSO

Smiles

CCCCCC[C@H](OC([C@@H]1CCCN1C(CNC(OC(C)(C)C)=O)=O)=O)CCC[C@@H]([C@H]2CC[C@@H](O2)[C@H]3CC[C@@H](O3)[C@@H](CCCCCCCCCCCCC4=C[C@@H](OC4=O)C)O)O

Molecular Formula

C49H84N2O11

Molecular Weight

877.20

References & Citations

[1]Jing-Fang Shi, et al. Synthesis and anticancer activity of Boc-Gly-Pro dipeptide-annonaceous acetogenin prodrugs targeting fibroblast activation protein or other hydrolytic enzymes. Medicinal Chemistry Research volume 31, pages605–616 (2022) .