Anticancer agent 30
Anticancer agent 30 (compound 6f-Z), a 3-arylidene-2-oxindole derivative, is a selective CDK2 inhibitor with potent anticancer activity[1].
Product Specifications
CAS Number
[2907774-88-1]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-30.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC2=CC=C(F)C=C2)C3=C(C=CC=C3)/C1=C/C4=CC=C(Cl)C=C4
Molecular Formula
C22H15ClFNO
Molecular Weight
363.81
References & Citations
[1]Hend A A Abd El-Wahab, et al. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies. Bioorg Chem. 2022 Jan 15;120:105622.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2
Curated Selection
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