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Anticancer agent 30

Anticancer agent 30 (compound 6f-Z), a 3-arylidene-2-oxindole derivative, is a selective CDK2 inhibitor with potent anticancer activity[1].

Product Specifications

CAS Number

2907774-88-1

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-30.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CC2=CC=C(F)C=C2)C3=C(C=CC=C3)/C1=C/C4=CC=C(Cl)C=C4

Molecular Formula

C22H15ClFNO

Molecular Weight

363.81

References & Citations

[1]Hend A A Abd El-Wahab, et al. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies. Bioorg Chem. 2022 Jan 15;120:105622.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK2

Frequently Asked Questions

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