Aldose reductase-IN-2
Aldose reductase-IN-2 (Compound 5f) is a potent inhibitor of aldose reductase (AR) . Aldose reductase-IN-2 has antioxidation capacity. Aldose reductase-IN-2 is a promising anti-diabetic complications agent[1].
Product Specifications
CAS Number
1687735-82-5
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aldose-reductase-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCNC([C@H](NC(C)=O)COCC1=CC=CC=C1)=O)/C(C#N)=C/C2=CC=C(O)C=C2
Molecular Formula
C25H28N4O5
Molecular Weight
464.51
References & Citations
[1]Liu Y, et al. Enhanced antioxidation capacity endowed to a mixed type aldose reductase inhibitor leads to a promising anti-diabetic complications agent [published online ahead of print, 2022 Jan 17]. Bioorg Chem. 2022;120:105624.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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