Anti-inflammatory agent 9

Anti-inflammatory agent 9 (compound 28) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 9 expresses activity on COX-2 enzyme more than COX-1. Anti-inflammatory agent 9 is orally active[1].

Product Specifications

CAS Number

[2910876-54-7]

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-9.html

Solubility

10 mM in DMSO

Smiles

CC1=C(SC2=NC3=CC=CC=C3N21)C(NNC(NC4=CC=CC=C4)=O)=O

Molecular Formula

C18H15N5O2S

Molecular Weight

365.41

References & Citations

[1] Darwish SA, et al. New tilomisole-based benzimidazothiazole derivatives as anti-inflammatory agents: Synthesis, in vivo, in vitro evaluation, and in silico studies [published online ahead of print, 2022 Jan 29]. Bioorg Chem. 2022;120:105644.