AChE-IN-8
AChE-IN-8 (Compound 19) is a potent inhibitor of AChE with an IC50 of 1.95 μM. AChE-IN-8 has the potential for the research of Alzheimer's disease[1].
Product Specifications
CAS Number
2919335-82-1
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-8.html
Solubility
10 mM in DMSO
Smiles
CCNC(N/N=C/C1=C2NC=C(C2=C(C=C1OC)OC)C3=CC=CC=C3)=S
Molecular Formula
C20H22N4O2S
Molecular Weight
382.48
References & Citations
[1]Yıldız M, et al. Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling [published online ahead of print, 2022 Jan 30]. Bioorg Chem. 2022;120:105647.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
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