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AChE-IN-8

AChE-IN-8 (Compound 19) is a potent inhibitor of AChE with an IC50 of 1.95 μM. AChE-IN-8 has the potential for the research of Alzheimer's disease[1].

Product Specifications

CAS Number

2919335-82-1

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-8.html

Solubility

10 mM in DMSO

Smiles

CCNC(N/N=C/C1=C2NC=C(C2=C(C=C1OC)OC)C3=CC=CC=C3)=S

Molecular Formula

C20H22N4O2S

Molecular Weight

382.48

References & Citations

[1]Yıldız M, et al. Dimethoxyindoles based thiosemicarbazones as multi-target agents; synthesis, crystal interactions, biological activity and molecular modeling [published online ahead of print, 2022 Jan 30]. Bioorg Chem. 2022;120:105647.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE

Frequently Asked Questions

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