NOS-IN-2
Product Specifications
UNSPSC Description
NOS-IN-2 (Compound 4i) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 20 μM, without inhibiting eNOS. NOS-IN-2 has little toxicity and can be used for studying inflammatory disorders[1].
Target Antigen
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nos-in-2.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C(C(CCNC(C2=CC=C(C=C2)C(F)(F)F)=N)O)=C1)N
Molecular Weight
367.37
References & Citations
[1]Fabio Arias, et al. Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors. Bioorg Med Chem. 2021 Aug 15;44:116294.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115916/NOS-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115916/
Clinical Information
No Development Reported
CAS Number
2766146-79-4
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