GPVI antagonist 3
GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI) . IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].
Product Specifications
CAS Number
901654-94-2
UNSPSC
12352005
Target
Glycoprotein VI
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gpvi-antagonist-3.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CCCO)C(C2=CC=C(OC)C=C2)C3=C1NN=C3C4=CC(C)=CC=C4O
Molecular Formula
C22H23N3O4
Molecular Weight
393.44
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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