GPVI antagonist 2
GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI) . IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent[1].
Product Specifications
CAS Number
880399-00-8
UNSPSC
12352005
Target
Glycoprotein VI
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gpvi-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CCCO)C(C2=CC=CC(OCCCC)=C2)C3=C1NN=C3C4=CC=CC=C4O
Molecular Formula
C24H27N3O4
Molecular Weight
421.49
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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