Antimalarial agent 9
Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity[1].
Product Specifications
CAS Number
2914224-54-5
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antimalarial-agent-9.html
Solubility
10 mM in DMSO
Smiles
COC1=NC2=CC=C(C=C2C=C1C(N3C=CN=C3)C4=CC(C(C)(C)C)=C(C(C(C)(C)C)=C4)O)Br
Molecular Formula
C28H32BrN3O2
Molecular Weight
522.48
References & Citations
[1]Roy D, et al. Synthesis, biological evaluation, Structure - Activity relationship studies of quinoline-imidazole derivatives as potent antimalarial agents. Bioorg Chem. 2022;121:105671.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
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