KRAS G12D inhibitor 3
KRAS G12D inhibitor 3 is a KRAS G12D inhibitor with an IC50 of [1]. KRAS G12D inhibitor 3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2757095-11-5]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12d-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
C#CC1=C(C=CC2=C1C(C3=C(C4=C(C(N5CC6CCC(N6)C5)=NC(OC[C@@]78CCCN7C[C@@H](C8)F)=N4)C=C3Cl)F)=CC(O)=C2)F
Molecular Formula
C34H31ClF3N5O2
Molecular Weight
634.09
References & Citations
[1]Xing DAI, et al. Quinazoline compounds, preparation methods and uses thereof. WO2022002102A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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