LDHA-IN-5
LDHA-IN-5 is a novel, potent, dual GO/LDHA inhibitor for primary hyperoxaluria.
Product Specifications
CAS Number
2776148-90-2
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ldha-in-5.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1F)CC2=C(N(N=C2C3=CC(SC4=C(N=NN4)C(O)=O)=CC=C3)C5=NC(C(O)=O)=CS5)CC6CC6)=O
Molecular Formula
C27H22FN7O6S3
Molecular Weight
655.70
References & Citations
[1]Ding J, et al. Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria. ACS Med Chem Lett. 2021 May 20;12 (7) :1116-1123.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LDHA
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