NMTCA

NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid. NMTCA can be used as an indicator of endogenous nitrosation by gas chromatography-thermalenergyanalysis[1][2].

Product Specifications

CAS Number

[103659-08-1]

Product Name Alternative

NMTPRO; N-Nitroso-2-methylthiazolidine 4-carboxylic acid; N-nitrosomethylthioproline

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/nmtca.html

Solubility

10 mM in DMSO

Smiles

CC1SCC(C(O)=O)N1N=O

Molecular Formula

C5H8N2O3S

Molecular Weight

176.19

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Ohshima H, et al. Presence in human urine of new sulfur-containing N-nitrosamino acids: N-nitrosothiazolidine 4-carboxylic acid and N-nitroso 2-methylthiazolidine 4-carboxylic acid. IARC Sci Publ. 1984; (57) :77-85.|[2]Tsuda M, et al. Increase in the levels of N-nitrosoproline, N-nitrosothioproline and N-nitroso-2-methylthioproline in human urine by cigarette smoking. Cancer Lett. 1986;30 (2) :117-124. |[3]Tsuda M, et al. Effect of cigarette smoking and dietary factors on the amount of N-nitrosothiazolidine 4-carboxylic acid and N-nitroso-2-methyl-thiazolidine 4-carboxylic acid in human urine. IARC Sci Publ. 1987; (84) :446-450.