3-Phenylpropyl isothiocyanate

3-Phenylpropyl isothiocyanate has a stronger inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis. 3-Phenylpropyl isothiocyanate has chemopreventive effects[1][2].

Product Specifications

CAS Number

[2627-27-2]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3-phenylpropyl-isothiocyanate.html

Solubility

10 mM in DMSO

Smiles

S=C=NCCCC1=CC=CC=C1

Molecular Formula

C10H11NS

Molecular Weight

177.27

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Morse MA, et al. Structure-activity relationships for inhibition of 4- (methylnitrosamino) -1- (3-pyridyl) -1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer Res. 1991;51 (7) :1846-1850.|[2]Nishikawa A, et al. Chemopreventive effects of 3-phenylpropyl isothiocyanate on hamster lung tumorigenesis initiated with N-nitrosobis (2-oxopropyl) amine. Jpn J Cancer Res. 1996;87 (2) :122-126.