1,2-Didecanoylglycerol
1,2-Didecanoylglycerol, a synthetic diacylglycerol, is metabolized by platelets to 1,2-didecanoylphosphatidic acid (PA10) and activates protein kinase C (PKC) [1][2].
Product Specifications
CAS Number
17863-69-3
UNSPSC
12352211
Target
PKC
Type
Reference compound
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/1-2-didecanoylglycerol.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCCCC)OCC(CO)OC(CCCCCCCCC)=O
Molecular Formula
C23H44O5
Molecular Weight
400.59
References & Citations
[1]Lapetina EG. Incorporation of synthetic 1,2-diacylglycerol into platelet phosphatidylinositol is increased by cyclic AMP. FEBS Lett. 1986;195 (1-2) :111-114. |[2]Negro-Vilar A, et al. 1,2-Didecanoylglycerol and phorbol 12,13-dibutyrate enhance anterior pituitary hormone secretion in vitro. Endocrinology. 1985;117 (4) :1559-1564.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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