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1,2-Didecanoylglycerol

1,2-Didecanoylglycerol, a synthetic diacylglycerol, is metabolized by platelets to 1,2-didecanoylphosphatidic acid (PA10) and activates protein kinase C (PKC) [1][2].

Product Specifications

CAS Number

17863-69-3

UNSPSC

12352211

Target

PKC

Type

Reference compound

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/1-2-didecanoylglycerol.html

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCCCCC)OCC(CO)OC(CCCCCCCCC)=O

Molecular Formula

C23H44O5

Molecular Weight

400.59

References & Citations

[1]Lapetina EG. Incorporation of synthetic 1,2-diacylglycerol into platelet phosphatidylinositol is increased by cyclic AMP. FEBS Lett. 1986;195 (1-2) :111-114. |[2]Negro-Vilar A, et al. 1,2-Didecanoylglycerol and phorbol 12,13-dibutyrate enhance anterior pituitary hormone secretion in vitro. Endocrinology. 1985;117 (4) :1559-1564.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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