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NAChR agonist 2

NAChR agonist 2 (compound 8) is a selective alpha4beta2 (α4β2) nAChR agonist (Kd=26 nM) [1].

Product Specifications

CAS Number

252870-46-5

UNSPSC

12352005

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nachr-agonist-2.html

Solubility

10 mM in DMSO

Smiles

C[C@H](NC)C/C=C/C1=CC=CN=C1

Molecular Formula

C11H16N2

Molecular Weight

176.26

References & Citations

[1]Huang X, et al. Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions. J Med Chem. 2006;49 (26) :7661-7674.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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