Nω-allyl-L-arginine
Product Specifications
UNSPSC Description
Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS). Nω-allyl-L-arginine can inactivate nNOS in a time-dependent manner. Nω-allyl-L-arginine also is a substrate, producing L-arginine, acrolein, and H2O[1][2].
Target Antigen
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nω-allyl-l-arginine.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](CCCNC(NCC=C)=N)C(O)=O
Molecular Weight
214.26
References & Citations
[1]Zhang HQ, et, al. Mechanism of Inactivation of Neuronal Nitric Oxide Synthase by Nω-Allyl-l-Arginine. J. Am. Chem. Soc. 1997, 119, 45, 10888-10902.|[2]Hah JM, et, al. Deuterium isotope effects and product studies for the oxidation of N(omega)-allyl-L-arginine and N(omega)-allyl-N(omega)-hydroxy-L-arginine by neuronal nitric oxide synthase. Bioorg Med Chem. 2000 Aug;8(8):1931-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115750/Nω-allyl-L-arginine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115750/
Clinical Information
No Development Reported
CAS Number
139461-37-3
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