Mant-GTPγS
Product Specifications
UNSPSC Description
Mant-GTPγS, a GTP mimetic, is a potent competitive adenylyl cyclase (AC) inhibitor. Mant-GTPγS is a potent YdeH inhibitor[1][2][3].
Target Antigen
Adenylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mant-gtpγs.html
Purity
93.0
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1NC)[穄.O=C2C(N=CN3[C@H]4[C@H](O[R])[C@H](O[R])[C@@H](COP(OP(OP(O)(O)=S)(O)=O)(O)=O)O4)=C3N=C(N)N2.[or].[H]
Molecular Weight
672.39
References & Citations
[1]Andreas Gille, et al. 2'(3')-O-(N-methylanthraniloyl)-substituted GTP analogs: a novel class of potent competitive adenylyl cyclase inhibitors. J Biol Chem. 2003 Apr 11;278(15):12672-9.|[2]Tomoharu Kanie, et al. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell. 2017 Jul 10;42(1):22-36.e12.|[3]Christian Spangler, et al. Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2',(3')-substituted purine and pyrimidine nucleotides. J Pharmacol Exp Ther. 2011 Jan;336(1):234-41.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-115748/Mant-GTPγS-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-115748/Mant-GTPγS-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
136749-24-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9340413-01 48 Well
Mouse Molybdenum cofactor biosynthesis protein 1 [Includes: Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor biosynthesis protein C], MOCS1 ELISA Kit
Ask
View Details ![Mouse Molybdenum cofactor biosynthesis protein 1 [Includes: Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor biosynthesis protein C], MOCS1 ELISA Kit](https://cdn.genprice.uk/genprice/genprice5.png)
MBS9340413-02 96 Well
Mouse Molybdenum cofactor biosynthesis protein 1 [Includes: Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor biosynthesis protein C], MOCS1 ELISA Kit
Ask
View Details ![Mouse Molybdenum cofactor biosynthesis protein 1 [Includes: Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor biosynthesis protein C], MOCS1 ELISA Kit](https://cdn.genprice.uk/genprice/genprice3.png)
MBS9340413-03 5x 96 Well
Mouse Molybdenum cofactor biosynthesis protein 1 [Includes: Molybdenum cofactor biosynthesis protein A; Molybdenum cofactor biosynthesis protein C], MOCS1 ELISA Kit
Ask
View Details