Xanthosine-5'-Triphosphate
Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide, is produced by deamination of purine bases. Xanthosine-5'-Triphosphate is a substrate of inosine triphosphate pyrophosphatase (ITPase) [1].
Product Specifications
CAS Number
6253-56-1
Product Name Alternative
5'-XTP
UNSPSC
12352005
Target
DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog; Phosphatase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/xanthosine-5-triphosphate.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N=C1)=C(N2)N1[C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)NC2=O
Molecular Formula
C10H15N4O15P3
Molecular Weight
524.17
References & Citations
[1]Davies O, et, al. Characterisation of multiple substrate-specific (d) ITP/ (d) XTPase and modelling of deaminated purine nucleotide metabolism. BMB Rep. 2012 Apr;45 (4) :259-64.|[2]Lin S, et al. Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. J Biol Chem. 2001 Jun 1;276 (22) :18695-701.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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